ASCOT

The ASCOT study was an investigator initiated study set up to compare different treatment strategies in the prevention of cardiovascular disease in patients who were hypertensive but were not considered conventionally dyslipidemic. The ASCOT study main results have been published in The Lancet.

A+ Science contribution

  • Design, power-calculation
  • Coordination and project leading
  • Database building
  • Center-selection, 686 sites in the Nordic countries
  • Recruitment of close to 10 000 patients
  • Monitoring on a smaller scale
  •  Endpoint adjudication (>10000 endpoints) and database
  •  ECG coding, handling and database with close to 60000 ECGs
  • Statistical analyses and medical report
  • FDA submission 

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Study details

  • cardiovascularclinical trial
  • Factorial design 
  • stopped early for benefit
  • conducted in 6 countries
  • close to 20 000 patients enrolled at more than 700 sites.

Read more

Main results published in The Lancet, Volume 366, Issue 9489, Pages 895 - 906
read summary

There are numeroues publications, find out more from the ASCOT webpage (the file found at the page requires excel).


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